The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Abnormal lung function/pulmonary physiology (PFTs) without necessarily imaging or clinical evidence
Publications
Electronic Cigarettes: Impact on Lung Function and Fractional Exhaled Nitric Oxide Among Healthy Adults.
American journal of men's health 2019 Jan-Feb;13;1557988318806073 — 2019 Jan-Feb — 1557988318806073
Ferrari M, Zanasi A, Nardi E, Morselli Labate AM, Ceriana P, Balestrino A, Pisani L, Corcione N, Nava S
Short-term effects of a nicotine-free e-cigarette compared to a traditional cigarette in smokers and non-smokers.
BMC pulmonary medicine 2015 Oct 12;15;120 — 2015 Oct 12 — 120
Short-term pulmonary effects of using an electronic cigarette: impact on respiratory flow resistance, impedance, and exhaled nitric oxide.
Chest 2012 Jun;141;1400-1406 — 2012 Jun — 1400-1406