The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pneumomediastinum
Publications
A Rare Case of Vaping-Induced Spontaneous Pneumomediastinum.
Cureus 2021 Aug;13;e17166 — 2021 Aug — e17166
Vaping associated lung injury: A potentially life-threatening epidemic in US youth.
Pediatric pulmonology 2020 Apr 06;; — 2020 Apr 06
Layden JE, Ghinai I, Pray I, Kimball A, Layer M, Tenforde M, Navon L, Hoots B, Salvatore PP, Elderbrook M, Haupt T, Kanne J, Patel MT, Saathoff-Huber L, King BA, Schier JG, Mikosz CA, Meiman J
Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin - Preliminary Report.
The New England journal of medicine 2019 Sep 06;; — 2019 Sep 06
Spontaneous Pneumomediastinum After Electronic Cigarette Use.
The Annals of thoracic surgery 2018 06;105;e269-e271 — 2018 06 — e269-e271