The Drug-Induced Respiratory Disease Website and App

E-cigarette - E-vaporizers - ENDS - Vaping - Dabbing

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LVIII.l

Path: Giant-cell interstitial pneumonia (GIP)-pattern

Hard metals in/from the heating element or wire may play a role

Publications

Fels Elliott DR, Shah R, Hess CA, Elicker B, Henry TS, Rule AM, Chen R, Golozar M, Jones KD

Giant cell interstitial pneumonia secondary to cobalt exposure from e-cigarette use.

The European respiratory journal 2019 Dec;54; — 2019 Dec

Henry TS, Kanne JP, Kligerman SJ

Imaging of Vaping-Associated Lung Disease.

The New England journal of medicine 2019 Sep 06;; — 2019 Sep 06