The Drug-Induced Respiratory Disease Website and App

E-cigarette - E-vaporizers - ENDS - Vaping - Dabbing

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.b

Pneumonitis (interstitial lung disease/ILD)

Publications

Fryman C, Lou B, Weber AG, Steinberg HN, Khanijo S, Iakovou A, Makaryus MR

Acute Respiratory Failure Associated With Vaping.

Chest. 2020;157(3):e63-e68

Hartnett KP, Kite-Powell A, Patel MT, Haag BL, Sheppard MJ, Dias TP, King BA, Melstrom PC, Ritchey MD, Stein Z, Idaikkadar N, Vivolo-Kantor AM, Rose DA, Briss PA, Layden JE, Rodgers L, Adjemian J

Syndromic Surveillance for E-Cigarette, or Vaping, Product Use-Associated Lung Injury.

The New England journal of medicine. 2020;382(8):766-772

Triantafyllou GA, Tiberio PJ, Zou RH, Lamberty PE, Lynch MJ, Kreit JW, Gladwin MT, Morris A, Chiarchiaro J

Vaping-associated Acute Lung Injury: A Case Series.

American journal of respiratory and critical care medicine. 2019;200(11):1430-1431

Itoh M, Aoshiba K, Herai Y, Nakamura H, Takemura T

Lung injury associated with electronic cigarettes inhalation diagnosed by transbronchial lung biopsy.

Respirology case reports. 2018;6(1):e00282