The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pulmonary edema, noncardiogenic (NCPE)
Patients with HCT-induced pulmonary edema may present with hypotension, shock, leukopenia and hemoconcentration. Rare PE cases are from HCT-induced left ventricular failure
Publications
A Rare Case of Pulmonary Edema Secondary to Hydrochlorothiazide Use.
Case reports in critical care 2024;2024;9423545 — 2024 — 9423545
Hydrochlorothiazide-induced systemic capillary leak.
The American journal of emergency medicine 2020 Feb 19;; — 2020 Feb 19
When a Diuretic Causes Pulmonary Oedema.
European journal of case reports in internal medicine 2018;5;000864 — 2018 — 000864
[Severe and rare adverse reaction to hydrochlorothiazide].
Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 2018 Oct-Dec;65;442-445 — 2018 Oct-Dec — 442-445
Recurrent Hydrochlorothiazide-Induced Acute Respiratory Distress Syndrome Treated With Extracorporeal Membrane Oxygenation.
The Journal of emergency medicine 2018 Dec;55;836-840 — 2018 Dec — 836-840
Hydrochlorothiazide-induced noncardiogenic pulmonary edema: BAL fluid analysis.
Chest 2011 Jan;139;193-4 — 2011 Jan — 193-4
Hydrochlorothiazide-associated noncardiogenic pulmonary oedema and shock: a case report and review of the literature.
Acta cardiologica 2007 Apr;62;215-20 — 2007 Apr — 215-20
Hydrochlorothiazide-induced noncardiogenic pulmonary edema: an underrecognized yet serious adverse drug reaction.
Pharmacotherapy 2005 Sep;25;1258-65 — 2005 Sep — 1258-65
Hydrochlorothiazide-induced pulmonary edema.
Southern medical journal 1999 Nov;92;1100-2 — 1999 Nov — 1100-2
Methaemoglobinaemia after inhalation of nitric oxide for treatment of hydrochlorothiazide-induced pulmonary oedema.
Lancet (London, England) 1996 Oct 12;348;1035-6 — 1996 Oct 12 — 1035-6
Pulmonary oedema and hypotension induced by hydrochlorothiazide.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 1994 Sep;49;308-10 — 1994 Sep — 308-10
Hydrochlorothiazide-induced pulmonary edema with severe acute myocardial dysfunction.
Clinical cardiology 1995 Feb;18;112-4 — 1995 Feb — 112-4
Acute idiosyncratic reaction to hydrochlorothiazide ingestion.
The Western journal of medicine 1983 Jan;138;101-2 — 1983 Jan — 101-2
Pulmonary edemafolloing ingestion of hydrochlorothiazide.
JAMA 1968 May 27;204;825-7 — 1968 May 27 — 825-7
Non-cardiogenic pulmonary edema after oral ingestion of hydrochlorothiazide.
Intensive care medicine 1987;13;364-5 — 1987 — 364-5
Hydrochlorothiazide causing unexplained pulmonary oedema.
The British journal of clinical practice 1989 Feb;43;79-81 — 1989 Feb — 79-81
Hydrochlorothiazide-associated pulmonary edema.
Chest 1989 Sep;96;695-7 — 1989 Sep — 695-7
Non-cardiogenic pulmonary edema after ingestion of chlorothiazide.
BMJ (Clinical research ed.) 1989 Mar 04;298;605 — 1989 Mar 04 — 605
Acute allergic interstitial pneumonitis induced by hydrochlorothiazide.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 1991 Jul 01;145;28-34 — 1991 Jul 01 — 28-34