The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Alveolar hemorrhage (AH), diffuse AH (DAH)
See also Long JL, et al. Diffuse Alveolar Hemorrhage Due to Electronic Cigarette Use. Am J Respir Crit Care Med 2016: Supplement A1862
Publications
Electronic cigarette use as a rare cause of diffuse alveolar hemorrhage.
Turkish journal of emergency medicine 2026;26 — 2026 — 142-145
Vaping-Associated Lung Injury With Suspected Diffuse Alveolar Haemorrhage: A Case Report.
Cureus 2025 Apr;17;e82799 — 2025 Apr
Villeneuve T, Prevot G, Le Borgne A, Colombat M, Collot S, Ruiz S, Lanot T, Brouchet L, Rabeau A, Noel-Savina E, Didier A
Diffuse alveolar haemorrhage secondary to e-cigarette "vaping" associated lung injury (EVALI) in a young European consumer.
The European respiratory journal 2020 Apr 07;; — 2020 Apr 07
Vaping-associated diffuse alveolar hemorrhage - A case report.
Respiratory medicine case reports 2020;30;101038 — 2020 — 101038
Vaping-induced diffuse alveolar hemorrhage.
Respiratory medicine case reports 2020;29;100996 — 2020 — 100996
Case 38-2019: A 20-Year-Old Man with Dyspnea and Abnormalities on Chest Imaging.
The New England journal of medicine 2019 Dec 12;381;2353-2363 — 2019 Dec 12 — 2353-2363
Diffuse Alveolar Hemorrhage Induced by Vaping.
Case reports in pulmonology 2018;2018;9724530 — 2018 — 9724530