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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XIX.b

BAL: An excess proportion of neutrophils

Publications

Harry-Hernandez S, Thiboutot J, Wahidi MM, Giovacchini CX, De Cardenas J, Meldrum C, Los JG, Illei PB, Shojaee S, Eissenberg T, DiBardino D, Giannini H, Maldonado F, Roller L, Yarmus LB, Kapp CM

Bronchoalveolar Lavage (BAL) and Pathologic Assessment of Electronic Cigarette or Vaping Product Use-associated Lung Injury (EVALI): The EVALI-BAL Study, A Multicenter Cohort.

Journal of bronchology & interventional pulmonology. 2023;30(2):144-154

Villeneuve T, Prevot G, Le Borgne A, Colombat M, Collot S, Ruiz S, Lanot T, Brouchet L, Rabeau A, Noel-Savina E, Didier A

Diffuse alveolar haemorrhage secondary to e-cigarette "vaping" associated lung injury (EVALI) in a young European consumer.

The European respiratory journal. 2020;56(1)

Marlière C, De Greef J, Gohy S, Hoton D, Wallemacq P, Jacquet LM, Belkhir L

Fatal e-cigarette or vaping associated lung injury (EVALI): a first case report in Europe.

The European respiratory journal. 2020;56(1)

Fryman C, Lou B, Weber AG, Steinberg HN, Khanijo S, Iakovou A, Makaryus MR

Acute Respiratory Failure Associated With Vaping.

Chest. 2020;157(3):e63-e68

Layden JE, Ghinai I, Pray I, Kimball A, Layer M, Tenforde MW, Navon L, Hoots B, Salvatore PP, Elderbrook M, Haupt T, Kanne J, Patel MT, Saathoff-Huber L, King BA, Schier JG, Mikosz CA, Meiman J

Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin - Final Report.

The New England journal of medicine. 2020;382(10):903-916