The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LVIII.r

Path: Alveolar hemorrhage (see also IIIa)

Separation or drug-induced AH from TBLB-related bleeding problematic in the single case described with the association (PMID 3124678)

Publications

Stein MG, Demarco T, Gamsu G, Finkbeiner W, Golden JA

Computed tomography: pathologic correlation in lung disease due to tocainide.

The American review of respiratory disease 1988 Feb;137;458-60 — 1988 Feb — 458-60