The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Sputum production - Bonchorrhea - ‘Bronchitis’
Publications
McConnell R, Barrington-Trimis JL, Wang K, Urman R, Hong H, Unger J, Samet J, Leventhal A, Berhane K
Electronic Cigarette Use and Respiratory Symptoms in Adolescents.
American journal of respiratory and critical care medicine. 2017;195(8):1043-1049
Subacute bronchial toxicity induced by an electronic cigarette: take home message.
Thorax. 2014;69(6):588
A case report of subacute bronchial toxicity induced by an electronic cigarette.
Thorax. 2014;69(6):596-7