The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Imaging: Alveolar opacities or haze with a batwing or butterfly distribution
PMID 34484520
Publications
E-Cigarette- or Vaping-Associated Lung Injury.
The New England journal of medicine. 2025;393(6):592
Casamento Tumeo C, Schiavino A, Paglietti MG, Petreschi F, Ottavianelli A, Onofri A, Cherchi C, Tomà P, Cutrera R
E-cigarette or Vaping product use Associated Lung Injury (EVALI) in a 15 year old female patient - case report.
Italian journal of pediatrics. 2022;48(1):119
Crazy vaping and crazy-paving, a case of E-Cigarette/Vaping-Associated Lung Injury (EVALI) with chest CT showing crazy-paving pattern.
Radiology case reports. 2021;16(11):3208-3212
Acute Respiratory Failure Associated With Vaping.
Chest. 2020;157(3):e63-e68
Vaping-associated Lung Injury.
Cureus. 2019;11(11):e6216