The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Acute respiratory failure (e.g. from ARDS, ILD, PIE, OP, pulmonary edema or bronchospasm) requiring ECMO
Publications
Hayes D, Board A, Calfee C, Ellington S, Pollack LA, Kathuria H, Eakin MN, Weissman DN, Callahan SJ, Esper AM, Crotty Alexander LE, Sharma NS, Meyer NJ, Smith LS, Novosad S, Evans ME, Goodman AB, Click ES, Robinson RT, Ewart G, Twentyman E
"Pulmonary and Critical Care Considerations for E-cigarette, or Vaping, Product Use-Associated Lung Injury (EVALI)".
Chest 2022 Mar 04;; — 2022 Mar 04
Villeneuve T, Prevot G, Le Borgne A, Colombat M, Collot S, Ruiz S, Lanot T, Brouchet L, Rabeau A, Noel-Savina E, Didier A
Diffuse alveolar haemorrhage secondary to e-cigarette "vaping" associated lung injury (EVALI) in a young European consumer.
The European respiratory journal 2020 Apr 07;; — 2020 Apr 07
Fatal e-cigarette or vaping associated lung injury (EVALI): a first case report in Europe.
The European respiratory journal 2020 Mar 26;; — 2020 Mar 26
Severe E-cigarette, or Vaping, Product Use Associated Lung Injury Requiring Venovenous Extracorporeal Membrane Oxygenation.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2020 Mar 06;; — 2020 Mar 06
Extracorporeal Membrane Oxygenation Support for Vaping-induced Acute Lung Injury.
The Annals of thoracic surgery 2020 Feb 27;; — 2020 Feb 27