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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XVI.b

Imaging: Ground-glass opacities (GGO) / shadowing

Publications

Schaffer S, Strang A, Saul D, Krishnan V, Chidekel A

Adolescent E-cigarette or Vaping Use-Associated Lung Injury in the Delaware Valley: A Review of Hospital-Based Presentation, Management, and Outcomes.

Cureus. 2022;14(2):e21988

Chidambaram AG, Dennis RA, Biko DM, Hook M, Allen J, Rapp JB

Clinical and radiological characteristics of e-cigarette or vaping product use associated lung injury.

Emergency radiology. 2020;27(5):495-501

Fryman C, Lou B, Weber AG, Steinberg HN, Khanijo S, Iakovou A, Makaryus MR

Acute Respiratory Failure Associated With Vaping.

Chest. 2020;157(3):e63-e68

Lu MA, Jabre NA, Mogayzel PJ Jr

Vaping-related Lung Injury in an Adolescent.

American journal of respiratory and critical care medicine. 2020;201(4):481-482

Ghinai I, Layden JE

Web Exclusive. Annals for Hospitalists Inpatient Notes - Clinical Pearls-E-Cigarette, or Vaping, Product Use-Associated Lung Injury.

Annals of internal medicine. 2019;171(12):HO2-HO3

Boloña E, Felix M, Vanegas E, Vera Paz C, Cherrez-Ojeda I

A Case of Vaping-associated Pulmonary Illness in South America: Highlighting the Need for Awareness and Surveillance Programs in the Region.

American journal of respiratory and critical care medicine. 2020;201(6):733-735

Viswam D, Trotter S, Burge PS, Walters GI

Respiratory failure caused by lipoid pneumonia from vaping e-cigarettes.

BMJ case reports. 2018;2018

McCauley L, Markin C, Hosmer D

An unexpected consequence of electronic cigarette use.

Chest. 2012;141(4):1110-1113