The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Flash (fulminate) pulmonary edema
May develop after first exposure to one single pill/tablet of drug
Publications
When a Diuretic Causes Pulmonary Oedema.
European journal of case reports in internal medicine 2018;5;000864 — 2018 — 000864
Hydrochlorothiazide-induced pulmonary edema and associated immunologic changes.
The Annals of pharmacotherapy 1999 Feb;33;172-4 — 1999 Feb — 172-4
Hydrochlorothiazide-induced acute pulmonary edema.
The Annals of pharmacotherapy 1995 Jul-Aug;29;701-3 — 1995 Jul-Aug — 701-3
Noncardiogenic pulmonary edema following hydrochlorothiazide ingestion.
Annals of emergency medicine 1987 Aug;16;901-3 — 1987 Aug — 901-3
[Hydrochlorothiazide-induced lung edema with shock].
Schweizerische medizinische Wochenschrift 1988 Jan 31;118;139-42 — 1988 Jan 31 — 139-42
Hydrochlorothiazide-induced pulmonary edema. Report of a case and review of the literature.
Archives of internal medicine 1979 Jul;139;817-9 — 1979 Jul — 817-9