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The Drug-Induced Respiratory Disease Website and App

XV.n

XV - Pathology

Path: Pulmonary alveolar proteinosis pattern (PAP pattern)

Last update 15/12/2014

Causative drugs

10

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

Anabolic androgenic steroids
I.j
I.n
II.b
II.d
II.f
III.a
IV.x
VI.e
X.u
XII.a
XII.c
XII.f
XII.g
XII.l
XII.o
XII.v
XII.ai
XV.n
XV.p
XV.bu
Busulfan
I.a
I.b
I.d
I.g
I.l
I.n
I.v
II.b
VI.b
XV.a
XV.c
XV.d
XV.f
XV.h
XV.i
XV.n
XV.bc
XVI.d
XVII.f
XIX.g
Cyclosporine
I.a
I.b
I.n
II.b
IV.k
VIII.a
X.c
X.f
XI.x
XIII.b
XV.a
XV.n
XVII.b
XVII.c
XVII.e
XVII.g
XVII.o
Dasatinib
I.b
I.d
I.n
I.y
II.a
V.a
V.c
V.d
V.h
V.i
V.m
VI.b
X.d
X.r
XI.b
XII.c
XV.c
XV.n
XV.ao
XV.ch
XVI.m
XVI.an
XIX.a
Fentanyl (smoked, snorted, insufflated, inhaled)
III.a
XV.n
XIX.e
Imatinib
I.a
I.b
I.c
I.d
I.m
I.n
I.y
II.b
II.d
III.a
V.a
V.c
V.i
V.m
V.ah
X.a
X.n
X.r
XII.a
XII.c
XII.f
XIII.g
XV.a
XV.c
XV.h
XV.n
XV.ch
XVI.ca
XVII.g
XVII.h
XVII.o
XVII.w
Marijuana, cannabis (haschish, hash, bang, dab)
I.a
I.c
I.e
I.j
I.n
I.t
I.an
I.ao
II.b
III.a
III.c
IV.a
IV.d
V.a
V.f
V.ab
VII.h
VIII.w
VIII.ax
IX.d
X.f
X.ac
XI.b
XI.j
XI.o
XI.ar
XII.c
XII.d
XII.g
XII.l
XII.s
XII.w
XII.af
XII.ap
XIII.a
XV.k
XV.n
XV.p
XV.q
XV.s
XV.v
XVI.m
XVI.ai
XVII.a
XVII.c
XVII.g
Mycophenolate mofetil
I.a
I.b
I.g
I.n
II.b
III.a
IV.d
IV.k
X.q
XV.g
XV.h
XV.n
XV.ab
XVII.e
XVII.g
Ruxolitinib
I.a
I.n
II.b
V.a
VI.b
IX.h
X.n
X.al
XI.d
XV.n
XVII.b
XVII.e
XVII.g
XVII.y
Sirolimus
I.a
I.b
I.d
I.f
I.l
I.m
I.n
II.b
III.a
IV.d
IV.l
IV.o
V.m
VI.a
VI.d
VI.f
VIII.a
X.c
XII.c
XV.c
XV.d
XV.e
XV.f
XV.g
XV.k
XV.m
XV.n
XV.ac
XV.bf
XVI.b
XVI.k
XVII.b
XVII.e
XIX.a