The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.e

ARDS - Acute lung injury

Publications

Shrestha NK, Mossad SB, Braun W

Pneumonitis associated with the use of mycophenolate mofetil.

Transplantation 2003 May 27;75;1762 — 2003 May 27 — 1762

Gross DC, Sasaki TM, Buick MK, Light JA

Acute respiratory failure and pulmonary fibrosis secondary to administration of mycophenolate mofetil.

Transplantation 1997 Dec 15;64;1607-9 — 1997 Dec 15 — 1607-9