The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Path: NSIP-cellular pattern (see also Ia, Ib)
Publications
Acute pulmonary complications in patients with hematologic malignancies.
Radiographics : a review publication of the Radiological Society of North America, Inc 2014 Oct;34;1755-68 — 2014 Oct — 1755-68
Challenging problems in advanced malignancy: Case 3. Imatinib mesylate-induced interstitial pneumonitis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003 Aug 15;21;3171-3 — 2003 Aug 15 — 3171-3