The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LIX.e

Pneumocystis jiroveci pneumonia

Publications

Russell TB, Rinker EK, Dillingham CS, Givner LB, McLean TW

Pneumonia During Sirolimus Therapy for Kaposiform Hemangioendothelioma.

Pediatrics 2018 04;141;S421-S424 — 2018 04 — S421-S424

Neff RT, Jindal RM, Yoo DY, Hurst FP, Agodoa LY, Abbott KC

Analysis of USRDS: incidence and risk factors for Pneumocystis jiroveci pneumonia.

Transplantation 2009 Jul 15;88;135-41 — 2009 Jul 15 — 135-41