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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XVII.c

Aspergillosis, pulmonary (invasive, allergic [ABPA], or mycetoma)

Publications

Gargani Y, Bishop P, Denning DW

Too many mouldy joints - marijuana and chronic pulmonary aspergillosis.

Mediterranean journal of hematology and infectious diseases. 2011;3(1):e2011005

Cescon DW, Page AV, Richardson S, Moore MJ, Boerner S, Gold WL

Invasive pulmonary aspergillosis associated with marijuana use in a man with colorectal cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2008;26(13):2214-5

Szyper-Kravitz M, Lang R, Manor Y, Lahav M

Early invasive pulmonary aspergillosis in a leukemia patient linked to aspergillus contaminated marijuana smoking.

Leukemia & lymphoma. 2001;42(6):1433-7

Cunnington D, Teichtahl H, Hunt JM, Dow C, Valentine R

Necrotizing pulmonary granulomata in a marijuana smoker.

Chest. 2000;117(5):1511-5

Marks WH, Florence L, Lieberman J, Chapman P, Howard D, Roberts P, Perkinson D

Successfully treated invasive pulmonary aspergillosis associated with smoking marijuana in a renal transplant recipient.

Transplantation. 1996;61(12):1771-4

Kagen SL, Kurup VP, Sohnle PG, Fink JN

Marijuana smoking and fungal sensitization.

The Journal of allergy and clinical immunology. 1983;71(4):389-93

Sutton S, Lum BL, Torti FM

Possible risk of invasive pulmonary aspergillosis with marijuana use during chemotherapy for small cell lung cancer.

Drug intelligence & clinical pharmacy. 1986;20(4):289-91

Denning DW, Follansbee SE, Scolaro M, Norris S, Edelstein H, Stevens DA

Pulmonary aspergillosis in the acquired immunodeficiency syndrome.

The New England journal of medicine. 1991;324(10):654-62

Chusid MJ, Gelfand JA, Nutter C, Fauci AS

Letter: Pulmonary aspergillosis, inhalation of contaminated marijuana smoke, chronic granulomatous disease.

Annals of internal medicine. 1975;82(5):682-3