The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LVII.a

BAL: An excess proportion of lymphocytes

Publications

Huang LK, Tsai MJ, Chang SC

Unusual radiological presentation of sirolimus-associated pneumonitis.

Journal of the Chinese Medical Association : JCMA 2013 Oct;76;588-92 — 2013 Oct — 588-92

Haydar AA, Denton M, West A, Rees J, Goldsmith DJ

Sirolimus-induced pneumonitis: three cases and a review of the literature.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004 Jan;4;137-9 — 2004 Jan — 137-9