The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.e

ARDS - Acute lung injury

Publications

Powell-Jackson PR, Carmichael FJ, Calne RY, Williams R

Adult respiratory distress syndrome and convulsions associated with administration of cyclosporine in liver transplant recipients.

Transplantation 1984 Oct;38;341-3 — 1984 Oct — 341-3

Carbone L, Appel GB, Benvenisty AI, Cohen DJ, Kunis CL, Hardy MA

Adult respiratory distress syndrome associated with oral cyclosporine.

Transplantation 1987 May;43;767-8 — 1987 May — 767-8

Bronsther O, Steiner R, Ward D, Gamboa E, Halasz N

Adult respiratory distress syndrome following intravenous cyclosporine.

Clinical transplants 1986;;128 — 1986 — 128

Walsh RF, Springate JE, Spivack BS, Mosovich LL, Anthone R, Anthone S, O'Shea M, Feld LG

Cyclosporine and adult respiratory distress syndrome.

Transplantation 1988 Nov;46;776-7 — 1988 Nov — 776-7