The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Lung cancer
A causal association is debated (PMID 24947688)
Publications
Zhang LR, Morgenstern H, Greenland S, Chang SC, Lazarus P, Teare MD, Woll PJ, Orlow I, Cox B, Cannabis and Respiratory Disease Research Group of New Zealand, Brhane Y, Liu G, Hung RJ
Cannabis smoking and lung cancer risk: Pooled analysis in the International Lung Cancer Consortium.
International journal of cancer. 2015;136(4):894-903
Marijuana use and risk of lung cancer: a 40-year cohort study.
Cancer causes & control : CCC. 2013;24(10):1811-20
Aldington S, Harwood M, Cox B, Weatherall M, Beckert L, Hansell A, Pritchard A, Robinson G, Beasley R, Cannabis and Respiratory Disease Research Group
Cannabis use and risk of lung cancer: a case-control study.
The European respiratory journal. 2008;31(2):280-6