The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pneumonitis (ILD)
Publications
Dasatinib-Related Pulmonary Toxicity Mimicking an Atypical Infection.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2016 Feb 20;34;e46-8 — 2016 Feb 20 — e46-8
Bergeron A, Réa D, Levy V, Picard C, Meignin V, Tamburini J, Bruzzoni-Giovanelli H, Calvo F, Tazi A, Rousselot P
Lung abnormalities after dasatinib treatment for chronic myeloid leukemia: a case series.
American journal of respiratory and critical care medicine 2007 Oct 15;176;814-8 — 2007 Oct 15 — 814-8
Dasatinib-related alveolar pneumonia responsive to corticosteroids.
Leukemia & lymphoma 2006 Jun;47;1180-1 — 2006 Jun — 1180-1