The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XX.e

Pneumocystis jiroveci pneumonia

Publications

Arts J, D'Haens G, Zeegers M, Van Assche G, Hiele M, D'Hoore A, Penninckx F, Vermeire S, Rutgeerts P

Long-term outcome of treatment with intravenous cyclosporin in patients with severe ulcerative colitis.

Inflammatory bowel diseases 2004 Mar;10;73-8 — 2004 Mar — 73-8

Quan VA, Saunders BP, Hicks BH, Sladen GE

Cyclosporin treatment for ulcerative colitis complicated by fatal Pneumocystis carinii pneumonia.

BMJ (Clinical research ed.) 1997 Feb 01;314;363-4 — 1997 Feb 01 — 363-4

Franson TR, Kauffman HM, Adams MB, Lemann J, Cabrera E, Hanacik L

Cyclosporine therapy and refractory Pneumocystis carinii pneumonia. A potential association.

Archives of surgery (Chicago, Ill. : 1960) 1987 Sep;122;1034-5 — 1987 Sep — 1034-5