The Drug-Induced Respiratory Disease Website and App

I. Interstitial/parenchymal lung disease

I.z Progression, acceleration or exacerbation of preexisting ILD/fibrosis

IV. Airway involvement

IV.a Bronchospasm - Wheezing - Asthma

V. Central-large-upper airway (incl. pharyngeal-nasal) involvement

V.a Angioedema (may cause UAO, asphyxia and death)

X. Systemic/Distant conditions, syndromes and reactions

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

XI. Miscellaneous

XI.b Chest pain (acute or subacute), lone or prominent

XIII. Esophageal involvement

XIII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

XIII. Esophageal involvement

XIII.d Esophageal toxicity

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (ILD)

I. Interstitial/parenchymal lung disease

I.z Progression, acceleration or exacerbation of preexisting ILD/fibrosis

I. Interstitial/parenchymal lung disease

I.ap Pulmonary infiltrates

II. Pulmonary edema - Acute lung injury - ARDS

II.e ARDS - Acute lung injury

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.c Hemoptysis

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.h Major/massive hemoptysis

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.l Alveolar hemorrhage, localized (e.g. lobar)

IV. Airway involvement

IV.n Bronchial wall erosion/hematoma

IV. Airway involvement

IV.ab Cough (lone)

IV. Airway involvement

IV.ak Bronchopericardial fistula

V. Central-large-upper airway (incl. pharyngeal-nasal) involvement

V.b Hematoma of/around central airway wall potentially causing UAO

V. Central-large-upper airway (incl. pharyngeal-nasal) involvement

V.d Laryngeal disorder-Laryngeal nerve palsy (dysphonia, hoarseness)

V. Central-large-upper airway (incl. pharyngeal-nasal) involvement

V.f Vocal cord dysfunction, adduction, closure, injury

VI. Pleural and/or pericardial involvement

VI.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

VI. Pleural and/or pericardial involvement

VI.e Hemothorax - Serosanguineous pleural effusion

VI. Pleural and/or pericardial involvement

VI.n Hemopericardium - Bloody pericardial effusion

VII. Pulmonary vasculopathy

VII.b Pulmonary arterial hypertension

VII. Pulmonary vasculopathy

VII.o Air/gas embolism

VII. Pulmonary vasculopathy

VII.y Pulmonary vein stenosis

VII. Pulmonary vasculopathy

VII.ab Pulmonary infarction

VII. Pulmonary vasculopathy

VII.ad Pulmonary vein perforation/rupture

VIII. Mediastinal involvement

VIII.d Fibrosing mediastinitis

VIII. Mediastinal involvement

VIII.g Hemomediastinum - Mediastinal hematoma

VIII. Mediastinal involvement

VIII.h Pneumomediastinum

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.j Phrenic nerve injury - Hemi- or bilateral diaphragmatic paralysis

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.n Vagal nerve injury (may cause GE reflux/GERD)

XI. Miscellaneous

XI.b Chest pain (acute or subacute), lone or prominent

XI. Miscellaneous

XI.i Esophageal hematoma (may cause chest pain and/or tracheal compression)

XII. Cardiovascular involvement / toxicity

XII.c Pericardial effusion (w/wo tamponade)

XII. Cardiovascular involvement / toxicity

XII.h Coronary artery disease (acute) - Myocardial ischemia/infarction

XII. Cardiovascular involvement / toxicity

XII.aa Pneumopericardium

XII. Cardiovascular involvement / toxicity

XII.ah Coronary vasospasm - Vasospastic angina

XII. Cardiovascular involvement / toxicity

XII.ay Postcardiac/-cardiotomy injury (PCIS-Dressler syndrome)

XII. Cardiovascular involvement / toxicity

XII.bg Perforation of the heart - Cardiac rupture

XII. Cardiovascular involvement / toxicity

XII.bj Atrio-esophageal fistula

XII. Cardiovascular involvement / toxicity

XII.bk Atrial septal defect, acquired

XII. Cardiovascular involvement / toxicity

XII.bn Pulmonary vein thrombosis

XII. Cardiovascular involvement / toxicity

XII.bz Pericardial-esophageal fistula

XIII. Esophageal involvement

XIII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

XVI. Imaging

XVI.b Imaging: Ground-glass opacities (GGO) / shadowing

XVI. Imaging

XVI.l Imaging: Peribronchovascular areas of consolidation

XVI. Imaging

XVI.bi Imaging: Pulmonary vein stenosis

XVI. Imaging

XVI.br Imaging: Localized calcification of pulmonary vein or veins

XIX. Pathology

XIX.r Path: Alveolar hemorrhage (see also IIIa)

XIX. Pathology

XIX.s Path: Pulmonary congestion

XIX. Pathology

XIX.bd Path: Pulmonary veno-occlusive disease (PVOD)

XIX. Pathology

XIX.da Path: Pulmonary vein stenosis

XX. Infections & related conditions

XX.a Respiratory tract infection incl. pneumonia

II. Pulmonary edema - Acute lung injury - ARDS

II.e ARDS - Acute lung injury

II. Pulmonary edema - Acute lung injury - ARDS

II.i Negative pressure pulmonary edema (NPPE)

IV. Airway involvement

IV.a Bronchospasm - Wheezing - Asthma

V. Central-large-upper airway (incl. pharyngeal-nasal) involvement

V.y Sinonasal discharge, -blockage, -obstruction

VII. Pulmonary vasculopathy

VII.a Pulmonary embolism - Venous thrombosis/thromboembolism

VII. Pulmonary vasculopathy

VII.l Acute pulmonary vasoconstriction and PHT

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.d Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)

X. Systemic/Distant conditions, syndromes and reactions

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

XI. Miscellaneous

XI.b Chest pain (acute or subacute), lone or prominent

XI. Miscellaneous

XI.h Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)

XI. Miscellaneous

XI.o Death following exposure or poisoning

XII. Cardiovascular involvement / toxicity

XII.ah Coronary vasospasm - Vasospastic angina

XIII. Esophageal involvement

XIII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

XX. Infections & related conditions

XX.a Respiratory tract infection incl. pneumonia

XX. Infections & related conditions

XX.b Opportunistic pulmonary/systemic infections

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (ILD)

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

I. Interstitial/parenchymal lung disease

I.n ILD with a granulomatous component

II. Pulmonary edema - Acute lung injury - ARDS

II.a Pulmonary edema, noncardiogenic (NCPE)

II. Pulmonary edema - Acute lung injury - ARDS

II.e ARDS - Acute lung injury

II. Pulmonary edema - Acute lung injury - ARDS

II.r Respiratory distress or failure, not otherwise specified

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

IV. Airway involvement

IV.x Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)

V. Central-large-upper airway (incl. pharyngeal-nasal) involvement

V.a Angioedema (may cause UAO, asphyxia and death)

V. Central-large-upper airway (incl. pharyngeal-nasal) involvement

V.c Upper airway obstruction other than angioedema or hematoma

V. Central-large-upper airway (incl. pharyngeal-nasal) involvement

V.w Uvulitis, uvular edema

VI. Pleural and/or pericardial involvement

VI.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

VI. Pleural and/or pericardial involvement

VI.v Eosinophilic pleuritis

VII. Pulmonary vasculopathy

VII.a Pulmonary embolism - Venous thrombosis/thromboembolism

VII. Pulmonary vasculopathy

VII.b Pulmonary arterial hypertension

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.a Diaphragm/inspiratory muscle weakness/paralysis (w/wo ARF)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.d Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)

X. Systemic/Distant conditions, syndromes and reactions

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

X. Systemic/Distant conditions, syndromes and reactions

X.w Multiple organ dysfunction/failure (MODS/MOF)

X. Systemic/Distant conditions, syndromes and reactions

X.y Eosinophilia myalgia syndrome (EMS)

XI. Miscellaneous

XI.b Chest pain (acute or subacute), lone or prominent

XI. Miscellaneous

XI.o Death following exposure or poisoning

XI. Miscellaneous

XI.bd Cyanide poisoning

XII. Cardiovascular involvement / toxicity

XII.d Myocarditis (can be fulminant)

XII. Cardiovascular involvement / toxicity

XII.g Cardiomyopathy (acute, subacute, chronic)

XII. Cardiovascular involvement / toxicity

XII.i Eosinophilic myocarditis

XII. Cardiovascular involvement / toxicity

XII.n Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

XII. Cardiovascular involvement / toxicity

XII.o Cardiovascular collapse - Cardiogenic shock - Hypotension

XII. Cardiovascular involvement / toxicity

XII.s Heart failure (biventricular, congestive)

XII. Cardiovascular involvement / toxicity

XII.t Heart block (bundle branch- or AV-)

XII. Cardiovascular involvement / toxicity

XII.u Cardiac- cardiorespiratory/pulmonary arrest

XII. Cardiovascular involvement / toxicity

XII.y Asystole

XII. Cardiovascular involvement / toxicity

XII.ai Bradycardia

XII. Cardiovascular involvement / toxicity

XII.aj Tachycardia

XII. Cardiovascular involvement / toxicity

XII.ak Cardiotoxicity

XIII. Esophageal involvement

XIII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

XVIII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

XVIII.d BAL: Gross or microscopic bleeding/hemorrhage

XIX. Pathology

XIX.d Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

XIX. Pathology

XIX.o Path: Diffuse alveolar damage (DAD-pattern) (see also IL)

XIX. Pathology

XIX.aq Path: Obliterative (constrictive) bronchiolitis (see also IVc, IVn)

XXVI. Veterinary medicine

XXVI.k Veterinary: Cardiotoxicity

XXVI. Veterinary medicine

XXVI.m Veterinary: Respiratory/Ventilatory depression

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (ILD)

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

I. Interstitial/parenchymal lung disease

I.ag Chemical (toxic) pneumonitis

II. Pulmonary edema - Acute lung injury - ARDS

II.r Respiratory distress or failure, not otherwise specified

IV. Airway involvement

IV.x Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)

V. Central-large-upper airway (incl. pharyngeal-nasal) involvement

V.i Thermal (burns, frostbite), chemical or caustic injury on the face, mouth, tongue, pharynx or upper airway

XIII. Esophageal involvement

XIII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

XIII. Esophageal involvement

XIII.c Esophageal stenosis/stricture

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (ILD)

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

I. Interstitial/parenchymal lung disease

I.e Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.g Pulmonary fibrosis

I. Interstitial/parenchymal lung disease

I.m Diffuse alveolar damage (DAD) (see alsoo under IIb and XVf)

I. Interstitial/parenchymal lung disease

I.x Rapidly progressive ILD/pulmonary fibrosis (Hamman-Rich syndrome)

I. Interstitial/parenchymal lung disease

I.bb Irreversible respiratory damage requiring lung Tx

II. Pulmonary edema - Acute lung injury - ARDS

II.e ARDS - Acute lung injury

II. Pulmonary edema - Acute lung injury - ARDS

II.f ARDS and the hemolytic-uremic syndrome (HUS)

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

IV. Airway involvement

IV.j Bronchiectasis

VI. Pleural and/or pericardial involvement

VI.f Pneumothorax

X. Systemic/Distant conditions, syndromes and reactions

X.w Multiple organ dysfunction/failure (MODS/MOF)

XI. Miscellaneous

XI.l Neutropenia, agranulocytosis (w/wo infection/sepsis)

XI. Miscellaneous

XI.o Death following exposure or poisoning

XIII. Esophageal involvement

XIII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

XVI. Imaging

XVI.k Imaging: An area or areas of consolidation

XVI. Imaging

XVI.n Imaging: Intralobular septal thickening - Crazy paving

XVI. Imaging

XVI.q Imaging: A pattern similar/consistent to/with IPF

XIX. Pathology

XIX.a Path: NSIP-cellular pattern (see also Ia, Ib)

XIX. Pathology

XIX.v Path: NSIP-fibrotic pattern

XXVI. Veterinary medicine

XXVI.f Veterinary: Acute Respiratory Distress Syndrome (ARDS)

XI. Miscellaneous

XI.b Chest pain (acute or subacute), lone or prominent

XI. Miscellaneous

XI.ap Pharmacobezoar

XIII. Esophageal involvement

XIII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

V. Central-large-upper airway (incl. pharyngeal-nasal) involvement

V.i Thermal (burns, frostbite), chemical or caustic injury on the face, mouth, tongue, pharynx or upper airway

XIII. Esophageal involvement

XIII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

XIII. Esophageal involvement

XIII.c Esophageal stenosis/stricture

XIV. Hemoglobinopathies - Abnormal hemoglobin states (acquired)

XIV.a Methemoglobinemia