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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

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Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Feng Y, Jing Z, Li Y, Lv S, Li W, Cai G, Yang D, Wang Y

Screening anaphylactoid components of Shuang Huang Lian Injection by analyzing spectrum-effect relationships coupled with UPLC-TOF-MS.

Biomedical chromatography : BMC. 2019;33(2):e4376

Zhan Q

Literature analysis of Acanthopanax anaphylactic shock in China.

Journal of traditional and complementary medicine. 2015;5(4):253-7

Meng WJ, Li Y, Zhou ZG

Anaphylactic shock and lethal anaphylaxis caused by compound amino acid solution, a nutritional treatment widely used in China.

Amino acids. 2012;42(6):2501-5

Wang L, Cui X, Cheng L, Yuan Q, Li T, Li Y, Deng S, Shang H, Bian Z

Adverse events to Houttuynia injection: A systematic review.

Journal of evidence-based medicine. 2010;3(3):168-76

Ji K, Chen J, Li M, Liu Z, Xia L, Wang C, Zhan Z, Wu X

Comments on serious anaphylaxis caused by nine Chinese herbal injections used to treat common colds and upper respiratory tract infections.

Regulatory toxicology and pharmacology : RTP. 2009;55(2):134-8

Ji KM, Li M, Chen JJ, Zhan ZK, Liu ZG

Anaphylactic shock and lethal anaphylaxis caused by Houttuynia Cordata injection, a herbal treatment in China.

Allergy. 2009;64(5):816-7