The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLVIII.d

Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)

Publications

Day R, Bradberry SM, Thomas SHL, Vale JA

Liquid laundry detergent capsules (PODS): a review of their composition and mechanisms of toxicity, and of the circumstances, routes, features, and management of exposure.

Clinical toxicology (Philadelphia, Pa.) 2019 Nov;57;1053-1063 — 2019 Nov — 1053-1063

Stromberg PE, Burt MH, Rose SR, Cumpston KL, Emswiler MP, Wills BK

Airway compromise in children exposed to single-use laundry detergent pods: a poison center observational case series.

The American journal of emergency medicine 2015 Mar;33;349-51 — 2015 Mar — 349-51