The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pulmonary arterial hypertension
Publications
Chinese herbal medicine Qing-Dai-induced pulmonary arterial hypertension in a patient with ulcerative colitis: A case report and experimental investigation.
Respiratory medicine case reports 2019;26;265-269 — 2019 — 265-269
Development of Pulmonary Arterial Hypertension in a Patient Treated with Qing-Dai (Chinese Herbal Medicine).
Internal medicine (Tokyo, Japan) 2019 Feb 01;58;395-399 — 2019 Feb 01 — 395-399
Chinese herbal drug natural indigo may cause pulmonary artery hypertension.
European heart journal 2016 07 01;37;1992 — 2016 07 01 — 1992
Sakurai Y, Tanabe N, Sekine A, Nishimura R, Jujo T, Kawasaki T, Sugiura T, Sakao S, Kasahara Y, Tatsumi K
Spontaneously remitted pulmonary arterial hypertension associated with the herbal medicine "bofutsushosan".
Internal medicine (Tokyo, Japan) 2013;52;1499-502 — 2013 — 1499-502
Severe pulmonary hypertension possibly due to pyrrolizidine alkaloids in polyphytotherapy.
Swiss medical weekly 2009 Apr 04;139;210-1 — 2009 Apr 04 — 210-1