The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.e

ARDS - Acute lung injury

ARDS due to alcohol is thought to occur primarily following aspiration (PMID 24811480)

Publications

Simou E, Leonardi-Bee J, Britton J

The Effect of Alcohol Consumption on the Risk of ARDS: A Systematic Review and Meta-Analysis.

Chest 2018 Jul;154;58-68 — 2018 Jul — 58-68

Lee A, Festic E, Park PK, Raghavendran K, Dabbagh O, Adesanya A, Gajic O, Bartz RR,

Characteristics and outcomes of patients hospitalized following pulmonary aspiration.

Chest 2014 Oct;146;899-907 — 2014 Oct — 899-907

Wind J, Versteegt J, Twisk J, van der Werf TS, Bindels AJ, Spijkstra JJ, Girbes AR, Groeneveld AB

Epidemiology of acute lung injury and acute respiratory distress syndrome in The Netherlands: a survey.

Respiratory medicine 2007 Oct;101;2091-8 — 2007 Oct — 2091-8

Guidot DM, Hart CM

Alcohol abuse and acute lung injury: epidemiology and pathophysiology of a recently recognized association.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2005 Jul;53;235-45 — 2005 Jul — 235-45