The Drug-Induced Respiratory Disease Website and App

Herbals - Dietary botanical therapy - Health products/food - Plants

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LI.n

Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

Publications

Sheth S, Tan EC, Tan HH, Tay L

Herb-induced cardiotoxicity from accidental aconitine overdose.

Singapore medical journal 2015 Jul;56;e116-9 — 2015 Jul — e116-9

Allen SF, Godley RW, Evron JM, Heider A, Nicklas JM, Thomas MP

Acute necrotizing eosinophilic myocarditis in a patient taking Garcinia cambogia extract successfully treated with high-dose corticosteroids.

The Canadian journal of cardiology 2014 Dec;30;1732.e13-5 — 2014 Dec — 1732.e13-5

Chen L, Titch T, Luo Z, Xu Y, Li X, Huang F, Liu L, Xiao W, Wu H, Wang Z

Confirmation of a proarrhythmic risk underlying the clinical use of common Chinese herbal intravenous injections.

Journal of ethnopharmacology 2012 Aug 01;142;829-35 — 2012 Aug 01 — 829-35