The Drug-Induced Respiratory Disease Website and App

Herbals - Dietary botanical therapy - Health products/food - Plants

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VIII.c

Upper airway obstruction other than angioedema or hematoma

Insoluble, needle-shaped abrasive oxalate crystals can be causative (PMID: 30262249)

Publications

Ceretto V, Nacca N

Mucosal Injury From Calcium Oxalate Crystals Resembling Anaphylaxis and Angioedema.

The Journal of emergency medicine. 2018;55(5):666-669

Caiozzi G, Cabrera D, Mardónez JM, Saldías F

[Herbal medicines and severe adverse effects: uvular angioedema caused by Echballium elaterium].

Revista medica de Chile. 2002;130(12):1407-10