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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.b

Pneumonitis (interstitial lung disease/ILD)

Causality assessment wide ranging

Publications

Komiya K, Mitsui MT, Watanabe T, Nasu M, Hiramatsu K, Kadota JI

Sansoninto-induced Lung Injury.

Internal medicine (Tokyo, Japan). 2022;61(24):3709-3712

Tahara M, Yamasaki K, Ikegami H, Fukuda Y, Uchimura K, Tachiwada T, Noguchi S, Kawanami T, Kido T, Mukae H, Yatera K

[A Case of Drug-Induced Lung Injury Caused by Kamikihito].

Journal of UOEH. 2019;41(1):51-56

Tsuchiya K, Toyoshima M, Suda T

Pneumonitis with Diffuse Alveolar Hemorrhage Induced by Sho-seiryu-to.

Internal medicine (Tokyo, Japan). 2017;56(19):2623-2626

Enomoto Y Md, Nakamura Y Md PhD, Enomoto N Md PhD, Fujisawa T Md PhD, Inui N Md PhD, Suda T

Japanese herbal medicine-induced pneumonitis: A review of 73 patients.

Respiratory investigation. 2017;55(2):138-144

Lim CY, Takano A, Yang S, Lee P

Ayurvedic medicine and the lung.

Respiration; international review of thoracic diseases. 2014;87(5):428-31

Imai Y, Morimoto K, Yoshimori K, Kurashima A, Ogata H, Kudoh S

[A case of drug-induced pneumonitis caused by saikokeishikankyoto].

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society. 2011;49(9):688-91