The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Diffuse alveolar damage (DAD) (see alsoo under IIb and XVf)
Publications
Piciucchi S, Romagnoli M, Chilosi M, Bigliazzi C, Dubini A, Beomonte Zobel B, Gavelli G, Carloni A, Poletti V
Prospective evaluation of drug-induced lung toxicity with high-resolution CT and transbronchial biopsy.
La Radiologia medica 2011 Mar;116;246-63 — 2011 Mar — 246-63
Sequential radiologic and functional pulmonary changes in patients with paraquat intoxication.
International journal of occupational and environmental health 2006 Jul-Sep;12;203-8 — 2006 Jul-Sep — 203-8