The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Rapidly progressive ILD/pulmonary fibrosis (Hamman-Rich syndrome)
Publications
[Acute pulmonary fibrosis associated with Paraquat poisoning. Report of one case].
Revista medica de Chile 2018 Jul;146;938-941 — 2018 Jul — 938-941
Paraquat - A deadly poison: Report of a case and review.
Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 2013 May;17;182-4 — 2013 May — 182-4
Bertram A, Haenel SS, Hadem J, Hoeper MM, Gottlieb J, Warnecke G, Kaschinski S, Hafer C, Kühn-Velten WN, Günther D, Kielstein JT
Tissue concentration of paraquat on day 32 after intoxication and failed bridge to transplantation by extracorporeal membrane oxygenation therapy.
BMC pharmacology & toxicology 2013 Sep 06;14;45 — 2013 Sep 06 — 45