The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XI.g

Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)

Publications

Lee A, Festic E, Park PK, Raghavendran K, Dabbagh O, Adesanya A, Gajic O, Bartz RR,

Characteristics and outcomes of patients hospitalized following pulmonary aspiration.

Chest 2014 Oct;146;899-907 — 2014 Oct — 899-907

Wilson KC, Saukkonen JJ

Acute respiratory failure from abused substances.

Journal of intensive care medicine 2004 Jul-Aug;19;183-93 — 2004 Jul-Aug — 183-93