The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

IV.a

Bronchospasm - Wheezing - Asthma

Publications

Ta V, White AA

Survey-Defined Patient Experiences With Aspirin-Exacerbated Respiratory Disease.

The journal of allergy and clinical immunology. In practice. 2015;3(5):711-8

Cardet JC, White AA, Barrett NA, Feldweg AM, Wickner PG, Savage J, Bhattacharyya N, Laidlaw TM

Alcohol-induced respiratory symptoms are common in patients with aspirin exacerbated respiratory disease.

The journal of allergy and clinical immunology. In practice. 2014;2(2):208-13.

Stefanutto TB, Halbach V

Bronchospasm precipitated by ethanol injection in arteriovenous malformation.

AJNR. American journal of neuroradiology. 2003;24(10):2050-1