Philippe Camus, M.D.

Dijon, France

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II.h

II - Pulmonary edema - Acute lung injury - ARDS

Hypoxemia, low oxygen saturation (may occur in isolation)

Last update 17/06/2026

(Fr: hypoxémie/désaturation isolée). Hypoxemia may reflect 1) Deteriorated VA/Q indicating early lung injury, cell sequestration in the distal pulmonary circulation 2) Ventilatory depression (see under IX a, c, d, e), in this case typically associated with a raise in arterial PCO2. See also under methemoglobinemia, a condition that commonly alters SpO2 readings. Rare instances of spurious hypoxemia from oxygen steal or larceny were described in high-WBC-acute leukemia patients receiving ATRA. Postoperative reopening of the foramen ovale may cause severe hypoxemia, sometimes positional (PMID 30619614)

Causative drugs

25

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Ado-trastuzumab emtansine
I.a
I.b
I.c
I.d
II.h
II.v
VII.b
All-transretinoic acid (ATRA)
I.a
I.l
II.a
II.e
II.h
II.l
III.a
VI.a
VI.m
VII.a
VII.d
X.q
X.ad
XII.c
Anabolic androgenic steroids
I.k
I.o
II.b
II.e
II.h
III.a
IV.ad
VII.e
X.w
XII.a
XII.c
XII.g
XII.h
XII.n
XII.p
XII.x
XII.ak
XIX.n
XIX.z
XIX.ci
Cardioversion (electrical)
II.b
II.c
II.h
II.k
Clevidipine
II.h
Codeine
II.a
II.h
IX.d
X.f
Epoprostenol
I.a
II.a
II.h
III.a
XII.o
Ethylene-vinyl alcohol copolymer (e.g. Onyx (R))
II.a
II.e
II.h
VII.t
XI.j
G/GM-CSF
I.a
I.b
I.c
II.a
II.e
II.h
IV.b
VI.a
VII.a
VII.e
X.c
X.q
X.aq
XI.b
XII.i
XII.av
XVIII.b
Hemodialysis - Chronic renal replacement therapy
I.c
I.g
I.j
II.h
II.j
VI.a
VI.c
VII.a
VII.b
VII.o
X.f
Hemotherapy (transfusion/infusion of whole blood, red cells, platelets, or blood products)
I.m
I.z
II.a
II.e
II.g
II.h
II.j
III.a
V.a
VII.a
VII.i
VII.n
X.f
XI.b
XI.e
XI.l
XII.k
XII.o
XVI.d
XIX.r
XIX.t
XIX.bj
XIX.bl
XX.ac
Hydrochloric acid fumes
I.ap
II.e
II.h
IV.a
IV.h
V.j
V.k
Hydrochlorothiazide
I.a
I.b
I.d
II.a
II.b
II.c
II.e
II.h
II.k
IX.h
X.b
X.c
X.d
X.e
X.w
XI.b
XII.c
XII.o
XII.u
XXIII.a
Iloprost
II.h
IV.a
VI.f
Ketamine
II.a
II.b
II.h
II.k
IV.a
V.h
IX.d
X.f
XI.b
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