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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XVI.d

Imaging: Alveolar opacities or haze with a batwing or butterfly distribution

Publications

Marchiori E, Hochhegger B, Zanetti G

Transfusion-related acute lung injury: an uncommon cause of pulmonary edema.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. 2023;49(4):e20230175

Carcano C, Okafor N, Martinez F, Ramirez J, Kanne J, Kirsch J

Radiographic manifestations of transfusion-related acute lung injury.

Clinical imaging. 2013;37(6):1020-3