The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.c

Capillary leak syndrome (CLS)

Publications

Tang JX, Luo GX, Zhu KE

[Capillary leak syndrome (CLS) induced by G-CSF: 3 cases report and literature review].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. 2012;33(4):334-6

Rechner I, Brito-Babapulle F, Fielden J

Systemic capillary leak syndrome after granulocyte colony-stimulating factor (G-CSF).

The hematology journal : the official journal of the European Haematology Association. 2003;4(1):54-6

de Azevedo AM, Goldberg Tabak D

Life-threatening capillary leak syndrome after G-CSF mobilization and collection of peripheral blood progenitor cells for allogeneic transplantation.

Bone marrow transplantation. 2001;28(3):311-2

Oeda E, Shinohara K, Kamei S, Nomiyama J, Inoue H

Capillary leak syndrome likely the result of granulocyte colony-stimulating factor after high-dose chemotherapy.

Internal medicine (Tokyo, Japan). 1994;33(2):115-9

Emminger W, Emminger-Schmidmeier W, Peters C, Susani M, Hawliczek R, Höcker P, Gadner H

Capillary leak syndrome during low dose granulocyte-macrophage colony-stimulating factor (rh GM-CSF) treatment of a patient in a continuous febrile state.

Blut. 1990;61(4):219-21