The Drug-Induced Respiratory Disease Website and App

Ethylene-vinyl alcohol copolymer (e.g. Onyx (R))

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XI.l

Superior vena cava syndrome

Publications

Crusio R, Ramachandran K, Ramachandran K, Kupfer Y, Tessler S

Superior vena cava syndrome caused by embolisation of liquid Onyx.

BMJ case reports 2011 Feb 14;2011; — 2011 Feb 14

Tawil I, Carlson AP, Taylor CL

Acute respiratory distress syndrome after onyx embolization of arteriovenous malformation.

Critical care research and practice 2011;2011;918185 — 2011 — 918185