The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Hypoxemia, low oxygen saturation (may occur in isolation)
Publications
The first 500: initial experience with widespread use of low-dose ketamine for acute pain management in the ED.
The American journal of emergency medicine 2015 Feb;33;197-201 — 2015 Feb — 197-201
Serious adverse events during procedural sedation with ketamine.
Pediatric emergency care 2009 May;25;325-8 — 2009 May — 325-8