The Drug-Induced Respiratory Disease Website and App

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.o Pulmonary alveolar proteinosis (PAP)

I. Interstitial/parenchymal lung disease

I.am Silicone pneumonitis - 'Silicone lung'

I. Interstitial/parenchymal lung disease

I.an Siliconoma

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.u Acute respiratory failure (e.g. from ARDS, ILD, PIE, OP, pulmonary edema or bronchospasm) requiring ECMO

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLV. Pleural and/or pericardial involvement

XLV.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

XLV. Pleural and/or pericardial involvement

XLV.w Silicone pleural effusion

XLV. Pleural and/or pericardial involvement

XLV.x Silicone pleural nodules - Pleural siliconomas

XLVII. Mediastinal involvement

XLVII.a Lymphadenopathy (intrathoracic)

XLVII. Mediastinal involvement

XLVII.e Granulomatous mediastinal lymphadenopathy

XLVII. Mediastinal involvement

XLVII.o Path: Silicone lymphadenopathy

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.e Autoimmunity-Autoimmune conditions (+ANA, +anti-ds-DNA, +ANCAs, other auto-Abs)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.j Eosinophilic granulomatosis with polyangiitis (Churg-Strauss)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.l Myopathy-Myositis-Polymyositis (see also under Xba)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.m Sarcoid-like granulomatosis (endo-/extrathoracic)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.o Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.s Systemic inflammatory response

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.u Vasculitis, pulmonary (w/wo AH), extrapulmonary, systemic: ANCA-positive

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.af Skin purpura, ecchymoses or necrosis

LI. Cardiovascular involvement / toxicity

LI.c Pericardial effusion (w/wo tamponade)

LV. Imaging

LV.k Imaging: An area or areas of consolidation

LV. Imaging

LV.ax Imaging: Displacement/migration of a breast implant

LV. Imaging

LV.bk Imaging: F18-PET scan positive lympadenopathy

LVI. Distinctive patterns - 'Eye-catchers'

LVI.c Eye catcher: A displaced breast implant

LVIII. Pathology

LVIII.af Path: Silicone droplets/vacuoles in lung tissue, pulmonary vasculature, or lymph nodes

LVIII. Pathology

LVIII.aj Path: Lymphoid hyperplasia (including nodular- or a lymphocytic interstitial pneumonia pattern)

LVIII. Pathology

LVIII.bq Path: Silicone pleural nodules or siliconoma (See under Vw)

LVIII. Pathology

LVIII.cx Path: Silicone lymphadenopathy

LX. Neoplastic conditions

LX.f Fibromatosis of the chest wall

LX. Neoplastic conditions

LX.h Pulmonary nodular lymphoid hyperplasia

LX. Neoplastic conditions

LX.i Breast implant-associated anaplastic large cell lymphoma

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

I. Interstitial/parenchymal lung disease

I.l Lung nodule or nodules

I. Interstitial/parenchymal lung disease

I.aa An area or areas of consolidation

I. Interstitial/parenchymal lung disease

I.am Silicone pneumonitis - 'Silicone lung'

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.u Acute respiratory failure (e.g. from ARDS, ILD, PIE, OP, pulmonary edema or bronchospasm) requiring ECMO

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.n Submucosal airway petechiae/hemorrhage

XLVI. Pulmonary vasculopathy

XLVI.m Silicone pulmonary embolism (SE) - SE syndrome

XLVII. Mediastinal involvement

XLVII.k Mediastinal silicone infiltration/siliconoma

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.w Multiple organ dysfunction/failure (MODS/MOF)

L. Miscellaneous

L.b Chest pain (acute or subacute), lone or prominent

L. Miscellaneous

L.d A restrictive lung function defect

L. Miscellaneous

L.x CNS symptoms or involvement, stroke

L. Miscellaneous

L.bk Parietal chest involvement

LV. Imaging

LV.b Imaging: Ground-glass opacities (GGO) / shadowing

LV. Imaging

LV.e Imaging: Pulmonary opacities with a subpleural distribution

LV. Imaging

LV.k Imaging: An area or areas of consolidation

LV. Imaging

LV.az Imaging: Foreign body pulmonary embolism

LV. Imaging

LV.bk Imaging: F18-PET scan positive lympadenopathy

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.d BAL: Gross or microscopic bleeding/hemorrhage

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.l BAL: Silicone globules in macrophages

LVIII. Pathology

LVIII.d Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

LVIII. Pathology

LVIII.o Path: Diffuse alveolar damage (DAD-pattern) (see also IL)

LVIII. Pathology

LVIII.r Path: Alveolar hemorrhage (see also IIIa)

LVIII. Pathology

LVIII.x Path: Pulmonary fibrosis (not otherwise specified or unclassifiable)

LVIII. Pathology

LVIII.af Path: Silicone droplets/vacuoles in lung tissue, pulmonary vasculature, or lymph nodes

LVIII. Pathology

LVIII.bh Path: Silicone pulmonary embolism

LVIII. Pathology

LVIII.ch Path: Siliconoma