The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Mediastinal silicone infiltration/siliconoma
Publications
Liquid Silicone-Induced Extensive and Debilitating Granulomatosis Responding to Hydroxychloroquine.
Case reports in rheumatology 2019;2019;8173790 — 2019 — 8173790
Direct migration of liquid silicone oil to the mediastinum.
The American journal of medicine 2008 Feb;121;e3-4 — 2008 Feb — e3-4