The Drug-Induced Respiratory Disease Website and App

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.d Acute eosinophilic pneumonia (AEP)

I. Interstitial/parenchymal lung disease

I.e Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.g Pulmonary fibrosis

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.a Pulmonary edema, noncardiogenic (NCPE)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.d Transient pulmonary opacities/infiltrates (see also under Iav)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLIII. Airway involvement

XLIII.a Bronchospasm - Wheezing - Asthma

XLIII. Airway involvement

XLIII.b Severe or catastrophic bronchospasm or asthma attack (can be fatal)

XLIII. Airway involvement

XLIII.x Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)

XLIII. Airway involvement

XLIII.ac Cough (acute, violent, explosive)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.a Angioedema (may cause UAO, asphyxia and death)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.i Thermal (burns, frostbite), chemical or caustic injury on the face, mouth, tongue, pharynx or upper airway

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.p Foreign body in the airway

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.q Drug foreign body in the airway

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.ad Retropharyngeal emphysema

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.aq Airway foreign body

XLV. Pleural and/or pericardial involvement

XLV.b Eosinophilic pleural effusion

XLV. Pleural and/or pericardial involvement

XLV.f Pneumothorax

XLV. Pleural and/or pericardial involvement

XLV.y Black pleural effusion

XLVI. Pulmonary vasculopathy

XLVI.a Pulmonary embolism - Venous thrombosis/thromboembolism

XLVII. Mediastinal involvement

XLVII.h Pneumomediastinum

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.ae Anti-GBM antibody disease (Goodpasture-like or flare of preexisting GS)

L. Miscellaneous

L.b Chest pain (acute or subacute), lone or prominent

L. Miscellaneous

L.c Pleuritic chest pain

L. Miscellaneous

L.bl Lung herniation

LI. Cardiovascular involvement / toxicity

LI.h Coronary artery disease (acute) - Myocardial ischemia/infarction

LI. Cardiovascular involvement / toxicity

LI.n Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

LI. Cardiovascular involvement / toxicity

LI.ac Arterial (aorta, limb) vasoconstriction and/or ischemia, acute

LI. Cardiovascular involvement / toxicity

LI.ag Aortic dissection

LV. Imaging

LV.b Imaging: Ground-glass opacities (GGO) / shadowing

LV. Imaging

LV.d Imaging: Alveolar opacities or haze with a batwing or butterfly distribution

LV. Imaging

LV.k Imaging: An area or areas of consolidation

LVI. Distinctive patterns - 'Eye-catchers'

LVI.l Eye catcher: Candy-cane esophagus

LVIII. Pathology

LVIII.b Path: Eosinophilic pneumonia (subacute or acute) (see also Ic)

LVIII. Pathology

LVIII.f Path: ILD with a granulomatous component (see also Im)

LVIII. Pathology

LVIII.r Path: Alveolar hemorrhage (see also IIIa)

LVIII. Pathology

LVIII.ab Path: Foreign body deposits/granulomatous reaction

LVIII. Pathology

LVIII.ac Path: Pneumoconiosis (silicosis, talcosis, talcoma)

LVIII. Pathology

LVIII.au Path: Airway inflammation

LVIII. Pathology

LVIII.ce Path: Alveolar carbonaceous material or deposits

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.b Pneumorenal syndrome (w/wo ANCAs)

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.c Hemoptysis

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.l Midline destructive lesions

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.m Perforation of the nasal septum

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.aj Nasal, palatal and/or pharyngeal pathology

XLV. Pleural and/or pericardial involvement

XLV.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

XLV. Pleural and/or pericardial involvement

XLV.m Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)

XLVI. Pulmonary vasculopathy

XLVI.b Pulmonary arterial hypertension

XLVI. Pulmonary vasculopathy

XLVI.d Pulmonary vasculitis or capillaritis

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.t CNS involvement/dysfunction/damage

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.l Myopathy-Myositis-Polymyositis (see also under Xba)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.q Neutrophilic dermatosis (Pyoderma, Sweet syndrome)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.u Vasculitis, pulmonary (w/wo AH), extrapulmonary, systemic: ANCA-positive

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.af Skin purpura, ecchymoses or necrosis

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.am Dual MPO-/PR3-ANCA systemic disease/vasculitis/pseudovasculitis

L. Miscellaneous

L.l Neutropenia, agranulocytosis (w/wo infection/sepsis)

L. Miscellaneous

L.o Death following exposure or poisoning

LI. Cardiovascular involvement / toxicity

LI.h Coronary artery disease (acute) - Myocardial ischemia/infarction

LI. Cardiovascular involvement / toxicity

LI.ac Arterial (aorta, limb) vasoconstriction and/or ischemia, acute

LV. Imaging

LV.b Imaging: Ground-glass opacities (GGO) / shadowing

LVI. Distinctive patterns - 'Eye-catchers'

LVI.t Eye catcher: Purpuric/Ecchymotic/Cyanotic lesions of the earlobes and/or nose

LVIII. Pathology

LVIII.ax Path: Pulmonary hypertension incl. angiomatoid vasculopathy

LVIII. Pathology

LVIII.cz Path: Skin vasculopathy/vasculitis/fibrin thrombi