The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VII.h

Pneumomediastinum

Publications

Blasco V, Nafati C, Reydellet L, Harti-Souab K, Albanèse J

[Spontaneous pneumomediastinum secondary to inhalation of crack].

Annales francaises d'anesthesie et de reanimation 2014 Apr;33;282-3 — 2014 Apr — 282-3

Janes SM, Ind PW, Jackson J

Images in Thorax. Crack inhalation induced pneumomediastinum.

Thorax 2004 Apr;59;360 — 2004 Apr — 360

Seaman ME

Barotrauma related to inhalational drug abuse.

The Journal of emergency medicine 1990 Mar-Apr;8;141-9 — 1990 Mar-Apr — 141-9