The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.a

Pulmonary edema, noncardiogenic (NCPE)

Publications

Ksienski D, Malhotra S, Walker B, Levy RD

Chest pain and cough in a 33-year-old postpartum woman.

Chest 2007 Oct;132;1389-92 — 2007 Oct — 1389-92

Laposata EA, Mayo GL

A review of pulmonary pathology and mechanisms associated with inhalation of freebase cocaine ("crack").

The American journal of forensic medicine and pathology 1993 Mar;14;1-9 — 1993 Mar — 1-9

Cucco RA, Yoo OH, Cregler L, Chang JC

Nonfatal pulmonary edema after "freebase" cocaine smoking.

The American review of respiratory disease 1987 Jul;136;179-81 — 1987 Jul — 179-81