The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Cherian SV, Sardinas G, Al Salihi SA, Barreda Garcia J

A 62-Year-Old Man with Cough and Dyspnea after Crack Cocaine Inhalation.

Annals of the American Thoracic Society 2016 Aug;13;1416-8 — 2016 Aug — 1416-8

Nadeem S, Nasir N, Israel RH

Löffler's syndrome secondary to crack cocaine.

Chest 1994 May;105;1599-600 — 1994 May — 1599-600

Kissner DG, Lawrence WD, Selis JE, Flint A

Crack lung: pulmonary disease caused by cocaine abuse.

The American review of respiratory disease 1987 Nov;136;1250-2 — 1987 Nov — 1250-2

Oh PI, Balter MS

Cocaine induced eosinophilic lung disease.

Thorax 1992 Jun;47;478-9 — 1992 Jun — 478-9