The Drug-Induced Respiratory Disease Website and App

Cathinones, synthetic ('Bath salts')

A recent epidemic. Including alpha-PVP and pentedrone and substituted cathinones. Can cause neurologic and CNS symptoms. Street name: 'bath salts'. PMID: 21899474, 22459606, 23827164, 24966713). Potassium permanganate used to synthetize the compound in the home may cause a parkinsonian syndrome (PMID 18322282)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX - Systemic/Distant conditions, syndromes and reactions

XLIX.l

Myopathy-Myositis-Polymyositis (see also under Xba)

L - Miscellaneous

L.o

Death following exposure or poisoning

LI - Cardiovascular involvement / toxicity

LI.g

Cardiomyopathy (acute, subacute, chronic)

LI.y

Asystole

LI.aj

Tachycardia