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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

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Pneumothorax

Publications

Nguyen HN, Das S, Gazzaneo MC, Melicoff E, Mallory GB, Eldin KW, Guillerman RP

Clinico-radiologic features of pleuroparenchymal fibroelastosis in children.

Pediatric radiology. 2019;49(9):1163-1170

Hendarsih E, Fadjari TH, Oehadian A

Chemotherapy-induced Spontaneous Pneumothorax: Case Series.

Acta medica Indonesiana. 2016;48(2):134-8

Chen JR, Yang YC

Spontaneous pneumothorax after intensive chemotherapy in endometrial cancer: a rare complication.

Taiwanese journal of obstetrics & gynecology. 2014;53(2):245-7

Bazan F, Vollmer I, Gayete A

Chemotherapy-induced secondary pneumothorax.

Archivos de bronconeumologia. 2014;50(1):44

Tamura T, Tamura S, Nasu H, Fujimoto T, Kinoshita T

[A case of intractable pneumothorax in a patient with pulmonary adenocarcinoma during bevacizumab-containing chemotherapy].

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society. 2011;49(9):702-6

Fehr M, von Moos R, Furrer M, Cathomas R

Spontaneous pneumothorax during chemotherapy: a case report.

Onkologie. 2010;33(10):527-30

Yamada N, Abe N, Usui K, Noda H, Tanaka Y, Tanai C, Ejima M, Ishihara T

[Clinical analysis of 12 cases of pneumothorax during intensive chemotherapy for malignant neoplasms].

Gan to kagaku ryoho. Cancer & chemotherapy. 2010;37(8):1519-23

Keijzer A, Kuenen B

Fatal pulmonary toxicity in testis cancer with bleomycin-containing chemotherapy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2007;25(23):3543-4

Jain TP, Thulkar S, Saha S, Bakhshi S, Dominic J

Extensive pneumothorax, pneumomediastinum and surgical emphysema as a complication of bleomycin therapy.

Pediatric radiology. 2005;35(12):1227-9

Parish JM, Muhm JR, Leslie KO

Upper lobe pulmonary fibrosis associated with high-dose chemotherapy containing BCNU for bone marrow transplantation.

Mayo Clinic proceedings. 2003;78(5):630-4

Stein ME, Haim N, Drumea K, Ben-Itzhak O, Kuten A

Spontaneous pneumothorax complicating chemotherapy for metastatic seminoma. A case report and a review of the literature.

Cancer. 1995;75(11):2710-3

Leeser JE, Carr D

Fatal pneumothorax following bleomycin and other cytotoxic drugs.

Cancer treatment reports. 1985;69(3):344-5

Kryger-Baggesen N

Spontaneous pneumothorax following regression of pulmonary metastases.

The European respiratory journal. 1990;3(4):485-6

Hsu JR, Chang SC, Perng RP

Pneumothorax following cytotoxic chemotherapy in malignant lymphoma.

Chest. 1990;98(6):1512-3

Biran H, Dgani R, Wasserman JP, Weissberg D, Shani A

Pneumothorax following induction chemotherapy in patients with lung metastases: a case report and literature review.

Annals of oncology : official journal of the European Society for Medical Oncology. 1992;3(4):297-300