Philippe Camus, M.D.
Dijon, France
In some countries it is believed that ILD develops in up to 2-4% of patients who receive the drug. Prior ILD may be a risk factor (PMID 25413260). Separating drug-induced ILD from disease progression, radiation pneumonitis, hemorrhage or an infection can be arduous. PMID 29174221
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
