The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.h

Subclinical pulmonary infiltrates/ILD

Publications

Ceylan KC, Kaya SO, Samancilar O, Gursoy S, Ucvet A

The effects of neoadjuvant chemotherapy on pulmonary structures: a quantitative analysis.

The Thoracic and cardiovascular surgeon. 2012;60(2):111-5

Busia A, Laffranchi A, Viviani S, Bonfante V, Villani F

Cardiopulmonary toxicity of different chemoradiotherapy combined regimens for Hodgkin's disease.

Anticancer research. 2010;30(10):4381-7

Yumuk PF, Kefeli U, Ceyhan B, Dane F, Eroglu BT, Gumus M, Cabuk D, Basaran G, Abacioglu U, Turhal NS

Pulmonary toxicity in patients receiving docetaxel chemotherapy.

Medical oncology (Northwood, London, England). 2010;27(4):1381-8

Leo F, Pelosi G, Sonzogni A, Chilosi M, Bonomo G, Spaggiari L

Structural lung damage after chemotherapy fact or fiction?

Lung cancer (Amsterdam, Netherlands). 2010;67(3):306-10

MacMahon H, Bekerman C

The diagnostic significance of gallium lung uptake in patients with normal chest radiographs.

Radiology. 1978;127(1):189-93